We are committed to transparency and the principles of open science. All our articles are published in peer-reviewed, open-access journals, ensuring free access to both the research findings and the underlying data. For broader public communication, please visit the communication page. Here, we focus exclusively on our scientific output.
Ketogenic interventions for brain health
Schrickel A., Groeneweg J., Dekeyster E. Exploring the potential of the ketogenic diet in autism spectrum disorder: metabolic, genetic, and therapeutic insights. Metabolic Brain Disease (2025) - download here
Dielemans DAM, van der Pluijm M, Yurtkap Y, Soeters MR, Oranje B, Smit DJA, Ziermans T, van Tricht MJ, Muthukumar S, Prasad S, van der Mieden van Opmeer RS, Dekeyster E, Kamperman AM, Dyck JRB, Rosema B, Hoekstra R, Kupka RW, de Haan L, van Beveren NJM, Huize K. The effect of exogenous ketones on signs and symptoms of schizophrenia spectrum or bipolar disorders: study protocol for a triple-blind, randomized, controlled cross-over pilot study. Current Development in Nutrition(2025) -download here
Schrickel A., Tinz R., van Vugt N., Blikkenhorst L., Huizer K., Jongkees B., Dekeyster E. The effect of ketogenic diet versus paleo diet on attention, mood, sleep quality, and cognition in undiagnosed woman. [manuscript in preparation, 2026]
Snel J, Ksvortsova A, Dekeyster E. The ketogenic diet improves the quality of life in patients with Autism Spectrum Disorder: a series of Case Reports. [manuscript in preparation, 2026]
Bezpalec D, Jongkees B, Struik N, Dekeyster E.Impact of Ketogenic Diet on ADHD symptoms and cognitive performance: a citizen science based approach. [manuscript in preparation, 2026]
Neuroscientific research
Geeraerts, E., Claes, M., Dekeyster, E., Salindas-Navarro, M., De Groef, L., Van den Haute, C., Scheyltjens, Il, Baekelandt, V., Arckens, L., Moons, L. Optogenetic stimulation of the superior colliculus confers retinal neuroprotection in a mouse glaucoma model. Journal of Neuroscience 17, 0872-18 (2019)
Elens, I., Dekeyster, E., Moons, L., D’Hooge, R. Methotrexate affects cerebrospinal fluid folate and Tau levels and induces late cognitive deficits in mice. Submitted to Neuropharmacology (2018)
De Groef, L.*, Dekeyster, E.*, Geeraerts, E., Salinas-Navarro, M., Moons, L. Differential visual system organization and susceptibility to experimental models of optic neuropathies in three commonly used mouse strains. *joined first authorship. Experimental Eye Research 145, 235-247 (2016)
Geeraerts, E., Dekeyster, E., Gaublomme, D., Salinas-Navarro, De Groef, L., M., Moons, L. A freely available semi-automated method for quantifying retinal ganglion cells in entire retinal flatmounts. Experimental Eye Research 147, 105-113 (2016)
Dekeyster, E., Geeraerts, E., Mebis, C., Buyens, T., Salinas-Navarro, M., De Groef, L., Moons, L. Tackling glaucoma from within the brain: an unfortunate interplay of BDNF and TrkB. PloS ONE 10, e0142067 (2015)
Dekeyster, E.*, Aerts, J., Valiente-Soriano, F.J., De Groef, L., Salinas-Navarro, M., VidalSanz, M., Arckens, L., Moons, L. Ocular hypertension results in retinotopic alterations in the visual cortex of adult mice. Current Eye Research 40, 1269-83 (2015)
Van houcke, J., De Groef, L., Dekeyster, E., Moons, L. The zebrafish as a gerontology model in nervous system aging, disease, and repair. Ageing Research Reviews 24, 358-368 (2015)
De Groef, L., Van Hove, I., Dekeyster, E., Stalmans, I., Moons, L. MMPs in the neuroretina and optic nerve: modulators of glaucoma pathogenesis and repair? Investigative Ophthalmology & Visual Science 55, 1953-1964 (2014)
Verslegers, M., Van Hove, I., Dekeyster, E., Gantois, I., Hu, T., D'Hooge, R., Arckens, L., Moons, L. MMP-2 mediates Purkinje cell morphogenesis and spine development in the mouse cerebellum. Brain Structure and Function 220, 1601-1617 (2014)
Verslegers, M., Van Hove, I., Buyens, T., Dekeyster, E., Knevels, E., Moons, L. Identification of MMP-2 as a novel enhancer of cerebellar granule cell proliferation. Molecular and Cellular Neurosciences 57, 63-72 (2013)
De Groef, L., Van Hove, I., Dekeyster, E., Stalmans, I., Moons, L. MMPs in the trabecular meshwork: promising targets for future glaucoma therapies? Investigative Ophthalmology & Visual Science 54, 7756-7763 (2013)
De Groef, L., Dekeyster, E., Gaublomme, D., Moons, L. Glaucoma from eye to brain: are MMP-2 and MMP-14 involved? Bulletin de la Société Belge d’Ophtalmology 320, 35-36 (2012)
Immunology
Roozendaal R., Hendriks J., van Effelterre T., Spiessens B., Dekking L., Solforosi L., Czapska-Casey D., Bockstal V., Stoop J., Splinter D., Janssen S., van Baelen B., Verbruggen N., Serroyen J., Dekeyster E., Volkmann A., Wollmann Y., Carrion R., Giavedoni L., Robinson C., Leyssen M., Douoguih M., Luhn K., Pau M, Sadoff J., Vandebosch A., Schuitemaker H., Zahn R., and Callendret B. Non-human primate to human immunobridging to infer the protective effect of an Ebola virus vaccine candidate. Npj Vaccines (2020)
Valayer S, Alexandre M, Prague M, Beavogui AH, Doumbia S, Kieh M, Greenwood B, Leigh B, Poupelin M, Schwimmer C, Sow SO, Berry IM, Kuhn JH, Fusco D, Cauwelaert ND, Watson-Jones D, Thiébaut R, Lévy Y, Yazdanpanah Y, Richert L, Lhomme E; PREVAC study team. Evaluation of waning of IgG antibody responses after rVSVΔG-ZEBOV-GP and Ad26.ZEBOV, MVA-BN-Filo Ebola virus disease vaccines: a modelling study from the PREVAC randomized trial. Emerg Microbes Infect 14(1) (2025)
Lee AW, Liu K, Lhomme E, Blie J, McCullough J, Onorato MT, Connor L, Simon JK, Dubey S, VanRheenen S, Deutsch J, Owens A, Morgan A, Welebob C, Hyatt D, Nair S, Hamzé B, Guindo O, Sow SO, Beavogui AH, Leigh B, Samai M, Akoo P, Serry-Bangura A, Fleck S, Secka F, Lowe B, Watson-Jones D, Roy C, Hensley LE, Kieh M, Coller BG; PREVAC Study Team. Immunogenicity and Vaccine Shedding After 1 or 2 Doses of rVSVΔG-ZEBOV-GP Ebola Vaccine (ERVEBO®): Results From a Phase 2, Randomized, Placebo-controlled Trial in Children and Adults. Clin Infect Dis. 78(4):870-879 (2024)
Wiedemann A, Lhomme E, Huchon M, Foucat E, Bérerd-Camara M, Guillaumat L, Yaradouno M, Tambalou J, Rodrigues C, Ribeiro A, Béavogui AH, Lacabaratz C, Thiébaut R, Richert L, Lévy Y; PREVAC study team. Long-term cellular immunity of vaccines for Zaire Ebola Virus Diseases. Nat Commun 15(1):7666 (2024) PREVAC Study Team; Kieh M, Richert L, Beavogui AH, Grund B, Leigh B, et al. Randomized Trial of Vaccines for Zaire Ebola Virus Disease. N Engl J Med. 29;387(26):2411-2424. (2022)
Badio M, Lhomme E, Kieh M, Beavogui AH, Kennedy SB, Doumbia S, Leigh B, Sow SO, Diallo A, Fusco D, Kirchoff M, Termote M, Vatrinet R, Wentworth D, Esperou H, Lane HC, Pierson J, Watson-Jones D, Roy C, D'Ortenzio E, Greenwood B, Chêne G, Richer L, Neaton JD, Yazdanpanah Y; PREVAC study team. Correction to: Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries. Trials; 22(1):583. (2021)
Badio M, Lhomme E, Kieh M, Beavogui AH, Kennedy SB, Doumbia S, Leigh B, Sow SO, Diallo A, Fusco D, Kirchoff M, Termote M, Vatrinet R, Wentworth D, Esperou H, Lane HC, Pierson J, Watson-Jones D, Roy C, D'Ortenzio E, Greenwood B, Chêne G, Richert L, Neaton JD, Yazdanpanah Y; PREVAC study team. Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries. Trials 23;22(1):86 (2021)
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